Sentence examples for mutations in linked from inspiring English sources

87, 96 However, in the case of tb1, there are also other mutations in linked loci that affect domestication traits.

The Breast Cancer Linkage Consortium has reported that approximately 70% of BRCA1 mutations and 90% of BRCA2 mutations in linked families are truncating mutations.

In regions of the genome with low recombination rates, mutations in linked genes compete for fixation (Hill and Robertson 1966), which has a similar effect as a lower effective population size.

Briefly, the method of Hudson and Kaplan ([ 10]; Equation (15)) allows one to estimate the expected reduction of neutral diversity in discrete intervals across a chromosome, with the effect of background selection on neutral diversity expressed as a function of the recombination rate and the proportion of sites subject to deleterious mutations in linked intervals.

These data provide direct evidence of mutations in spike linked with development of FIP in cats.

In addition, these results highlight new patho-physiological mechanisms for intellectual disabilities associated to mutations in RhoGTPases linked genes.

DiMauro and Schon (8) were the first to describe criteria for the identification of mutations in mtDNA linked to disease.

Our analysis identifies genes under positive selection and bowhead-specific mutations in genes linked to cancer and aging.

We propose a temporal comprehensive model in which two mutations in two linked genes could be players in sex determination and indirectly establish the Vitis domestication process.

In that regard, recent studies on hereditary prostate cancer (HPC1), positioning at the locus 1q24-q25, found two rare heterozygous inactivating germline mutations in RNASEL linked to HPC1.

Moreover, in our studies the expression of various point mutations in Vav2 linked the signaling directly to growth factor receptors and PI3-K.