Sentence examples for mutations in just from inspiring English sources

This strategy resulted in a total of six stabilizing mutations in just two generations with three mutations per generation.

Indeed, repairing the mutations in just the three DNA repair genes completely removed the radiation resistance.

Of these 10 families, 5 present mutations in both alleles, whereas the remaining 5 have mutations in just one allele.

Nearly 96% of these patients had mutations in just four genes (PMP22, MPZ, GJB1 and MFN2) linked to CMT.

Importantly, the link dynamics is asymmetric, i.e., the evolutionary steps are mutations in just one of the binding parters.

Decher et al. found that mutations in just one of the four subunits making up the tetrameric Kv structure were sufficient to block the effect of the fatty acids, suggesting a single fatty acid binding site per channel.

Eventually the researchers searched for people who had a mutation in just one copy of TREM2.

Furthermore, both mice and humans harboring a germ-line inactivating mutation in just one allele of the p53 gene develop tumors early in life and at very high frequencies [2]-[5].

Hence mutations in both genes might be expected to offer a selective advantage over a mutation in just one of them.

Although Heravi-Moussavi et al (2012) found a hotspot mutation in 1/14 testicular GCTs analysed, De Boer et al (2012) identified a mutation in just 1/96 tumours.

Interestingly, this treatment was successfully applied on an Ataxia-telangiectasia patient with heterozygous nonsense mutation, thereby demonstrating therapeutic ability despite the presence of a nonsense mutation in just one allele [Nakamura et al., 2011].