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It meant we could get on with understanding how mutations in it led to breast cancer.
For a concise description of the process of adaptation and the role of beneficial mutations in it, see Orr, H. A. 2003.
Fruit flies with mutations in it have atrophied muscles, and in people, similar mutations lead to frequent muscle cramps.
Mutations in it can cause various degrees of pigmentation.
The program commits itself to a particular stem according to its composition especially with respect to the number of covarying mutations in it.
This gene is essential for cartilage tissue development and mutations in it have been associated with Stickler syndrome type III and Marshall syndrome [46], which are characterized by hearing loss and bone and joint defects.
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As the virus jumped from person to person, about half the time it had a mutation in it, which caused one of the proteins in the virus to be slightly different.
This is because one isolate had more than one mutation in it which therefore increased the number of mutations that are seen in Table 5.
The avian virus would need to accumulate many mutations in its genetic material before it could become a pandemic strain, said Yoshihiro Kawaoka, a virologist at the University of Tokyo and the University of Wisconsin.
The algorithm differs from other techniques to distinguish drivers from other mutations in that it considers not only how often the gene is mutated in different tumors, but also the manner in which it is mutated.
Given the clear importance of histone mutations in pHGG, it will be interesting to see how aberrant epigenetic regulation contributes to tumorigenesis in the pediatric context.
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