Sentence examples for mutations in greater from inspiring English sources

In the next section, we follow the same general approach, but focusing on a different set of epistatic interactions, to examine differences between individual mutations in greater detail.

We characterized two mutations in greater detail, one in the plug (R66I) and the other at the lumenal end of TM3 (M136TM3

We characterized nine of these mutations in greater detail by assessing transcript levels throughout development, morphological changes in the mushroom bodies, and restoration of control levels of aggression in revertant alleles.

The Typhimurium model would permit a degree of experimental flexibility in understanding these mutations in greater detail, but may not precisely reflect the effects seen during acute typhoid fever in humans.

This led us to investigate the effect of the Rpn1-D517A mutatinn in greater detail.

p53 has been reported to be frequently mutated in humans cancers with mutations occurring in greater than 50% of lung tumors [ 135, 136].

Another mutation appeared in greater than 50% of the population, in phnN (fig. 3 B).

Subsequent WB analysis revealed that degradation of WT protein was faster than that of K346T, particularly after 12 h of cycloheximide treatment (Fig.  4A and B), suggesting that the p.K346T mutation results in greater protein stability.

First, the presence of TP53 mutations in the great majority of CNS metastatic lesions implies that therapeutic strategies aimed at exploiting loss of p53 function could be highly effective in brain metastasis, even if the primary breast cancer is wild type for TP53.

This finding makes sense because r is the mutation rate per site, and longer gene sequences accumulate more mutations and result in greater degrees of divergence between the genes involved in a WGD pair.

In just the same way, different experiences in different parts of the world favored genetic mutations selectively, resulting in greater or lesser energy efficiency, and other variations in metabolism influencing the propensity to gain, retain, or lose weight.