Sentence examples for mutations in experiments from inspiring English sources

Moreover, we illustrate that YLoc can be applied to explain localization changes caused by mutations in experiments.

We resequenced all identified mutations in independent experiments.

We measured the fitness effect of each of the three mutations in competition experiments at 42.2°C in DM25.

The authors used a different approach (pulsed nutlin-3 exposure) and detected different p53 mutations in different experiments.

These findings imply that E. coli rarely acquires two or more QRDR mutations in MPC experiments performed under static conditions.

For example, modeling the frequency of emergence of compensatory mutations in the experiments the authors concluded that an average deleterious mutation can be compensated by ∼9 different substitutions [ 57].

The final proof of the causative role of the mutation came in experiments in which Pollak's group showed that, when the mutant gene was 'knocked-in' in mice, the animals developed FSGS, showing that this gene defect alone is capable of causing the disease [ 9].

Instead, we argue that positive selection was able to drive the fixation of beneficial mutations in our experiment.

Thus, the proportion of offspring that carried new ry mutations in each experiment was equivalent to the frequency of mutation at the target.

For instance, [ 30] observed the occurrence of 66 new advantageous mutations in an experiment of E. coli culture over 1000 generations.

The authors used protein-stability estimates to predict the fitness effects of mutations in their experiment and found that this provided a better fit than all the classical distributions tested.