Sentence examples for mutations in experimental from inspiring English sources

Identification of the responsible mutant genes and of the functional consequences of the mutations in experimental preparations have begun to shed light on mechanisms underlying a rare form of partial epilepsy in humans, autosomal dominant nocturnal frontal lobe epilepsy.

GroEL can buffer slightly deleterious mutations in experimental setups.

This is surprising given the transforming effect of PIK3CA mutations in experimental systems.

These studies demonstrate the feasibility of identifying adaptive mutations in experimental populations.

A recent study by Bose and colleagues suggests that another subset of breast cancer patients without HER2 amplification but with activating HER2 mutation might also benefit from existing HER2-targeted agents and the authors functionally characterize these somatic mutations in experimental models.

Among the different reactions catalyzed by CYP1A1, hydroxylation at a vacant position of an aromatic ring is considered to be the hallmark for the initiation of carcinogenesis, through the formation of highly reactive conversion products that can cause oncogenic mutations in experimental animals and humans [ 1, 2].

We chose to apply our method to the U1685C mutation in experimental line 3, which rose rapidly in frequency once it appeared and is therefore likely to have a particularly large selection coefficient (see Figure 5A).

Mutations present in experimental data are experimentally induced and also non-experimentally induced.

An alternative way to calibrate molecular clocks for estimating the age of bacterial lineages is to determine directly the rates at which mutations accumulate in experimental systems [ 19- 21].

More generally, that we have uncovered an example of adaptive evolution driven by the substitution of two synonymous mutations in an experimental system evolving over a few hundred generations suggests that this class of mutation may be an underappreciated cause of adaptation and evolutionary dynamics in nature.

Analysis of double mutations in inbred experimental organisms suggests some principles for gene interaction that may apply to natural variation as well.