Sentence examples for mutations in developing from inspiring English sources

Worth considering is that environmental induced epigenetic mutations in developing germ cells may have consequences for lifetime fertility as there is likely to be plasticity in histone modifications.

We suggest that continuous minimal inhibition of MAPK signalling might be sufficient to prevent some of the developmental features caused by CFC mutations in developing children.

Based on the observation that CSPG domains can interact with PDGF proteins and that epidermal blistering caused by Fras/Frem gene mutations in developing blebs mice is ultrastructurally, spatially and temporally similar to that observed in PdgfC mutants, we hypothesised that FREM1 might regulate the capacity of PDGFC to regulate downstream remodelling of the extracellular matrix (ECM).

Our observation provides an experimental case that autoimmune disease may be induced by acquired mutation in developing T cells.

The spastin mutation in developing pupal eyes causes a mild mislocalization of the apical membrane domain at the distal section, but the apical domain was dramatically reduced at the proximal section of the developing pupal eye.

SM-like revertants had a higher growth rate than WS and no longer expressed significant amounts of cellulose, further confirming that the expression of this high-cost polymer was the basis of maladaptation and the target of compensatory mutation in developing colonies.

For instance, among the few commonly deregulated genes identified after Insm1 mutation in developing and mature β-cells, we identified Insulin-1 (Ins1) that was downregulated twofold and 13-fold after mutation of Insm1 in adult and developing β-cells, respectively.

Identifying pathways activated by RAS mutations could help in developing targeted treatments for tumors with RAS mutations [ 39].

This mobile phone-assisted decoding platform provides an effective but economic mutation detection alternative for the future quicker and sensitive detection of virtually any mutation-related diseases in developing and underdeveloped countries.

The answer isn't known, but the acquisition of somatic mutations in the developing brain could, in principle, be part of the answer.

Prolific mutations, which viruses undergo in developing new strains to evade either migrational, vaccination programmatic (influenza), or pharmaceutical (HIV) pressures, seem complex and inaccessible to engineering methods.