Sentence examples for mutations in control from inspiring English sources

Previously described mutations in control cell lines were detected.

14 15 The aim of this study was to determine the frequency of ABCA4 mutations in control individuals.

All CAN1 mutations in control cells and 33/36 CAN1 region mutations in KanMX-ISceIRS cells occur at the canonical APOBEC3G C C context.

The co-segregation with ASD seen in three of the four families and the scarcity of the three novel missense mutations in control subjects is consistent with rare variants of this gene playing a role in ASD susceptibility.

We report a phylogenetic tree constructed from the whole genome sequencing of twenty-three Indiandand one Ethiopian M lineage to resolve some of the anomalies occurring due to recurrent mutations in control region.

We are currently investigating the transcriptional changes that are induced by cic mutations in control and rbf1 mutant backgrounds to determine if Cic regulates different transcriptional programs depending on the status of RBF1.

A significantly higher number of G mutations was indeed observed in the WRC or GYW motifs in NBS patients (Fig. 2 and Table 2), whereas G residues outside these motifs were targeted equally (11.3% vs. 11.1% of total mutations in controls).

On the other hand, also for complexes III and V, Danes and southern Europeans had a similar trend with more nonsynonymous mutations in controls than in ultranonagenarians, while Finns showed no differences between ultranonagenarians and controls for both complexes.

However, complex I exhibited higher mutation frequency in the 90+ group than in controls in Finns (suggesting that mutations in these subunits may be beneficial), but it showed more mutations in controls than in 90+ in Danish and in southern Europeans (suggesting that mutations in the subunits of complex I may be detrimental).

For complex III and V, Danish and southern European populations showed a higher frequency of mutations in controls than in the 90+ group (P = 0.005 in Denmark and P = 0.048 in South Europe) (P = 0.0011 and P = 0.0023, respectively), while in the Finnish population, the mutation frequency did not differ between the 90+ and controls for both complexes.

As shown for treated participants in Figure 3A, 8 of 11 comparisons revealed an accumulation of mutations, whereas in control participants depicted in Figure 3C, only 2 of 10 had an accumulation of mutations over the study period.