Sentence examples for mutations in cellular from inspiring English sources

Changes in regulation of protein expression, loss of function of a cell, or even uncontrollable division can occur if mutations in cellular DNA go uncorrected.

But if the mother carries harmful genetic mutations in cellular structures called mitochondria, scientists would remove her unhealthy mitochondria and substitute those of a second woman so the baby would not inherit a potentially devastating "mitochondrial disease".

EBV-susceptible transgenic mice or primary murine cells, which carry a priori defined genetic mutations in cellular genes presumably involved in EBV's pathogenesis, would be valuable tools and greatly advance our understanding of the functions of cellular and viral gene products and their critical interplay.

Currently, a thorough investigation of the roles of these mutations in cellular tolerance to alkanes is lacking.

In addition, Tax BLV inhibits base-excision DNA repair of oxidative damage, potentially increasing the accumulation of ambient mutations in cellular DNA [ 13].

There is accumulating evidence that the multistage carcinogenic process is associated with the progressive acquisition of mutations in cellular proto-oncogenes and in growth-suppressor genes.

Blocking Parp-1 activity with specific inhibitors, or through null mutations, results in cellular hypersensitivity to DNA damaging agents and defects in DNA repair (Herceg and Wang, 2001).

The germline mtDNA sequence determined using DNA isolated from the patient's blood (control) was compared to the mutations present in cellular mtDNA recovered from patient's NAF.

The matter is that carcinogenesis is closely related to cellular proliferation: due to cell divisions, accumulation of mutations in the cellular genome is possible (see below).

To characterize these mutations in a cellular assay we measured the ability of the mutated proteins to transport a model intracellular effector protein, LFN-DTA, to the cytosolic compartment of CHO-K1.

Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes.