Sentence examples for mutations impact other from inspiring English sources
The LGI1 mutation in one ADPEAF family has been correlated with hyperactivity (Berghuis et al., 2013), and it will be important to determine if LGI1 mutations impact other diseases of synaptic connectivity.
This €25 million will impact other projects.
To impact others positively?
Studies on the KE family have also included formal evaluations of non-verbal intelligence and the average IQ of affected KE family members is lower than that of unaffected individuals (Fisher et al. 1998; Vargha-Khadem et al. 1995; Watkins et al. 2002a), raising the possibility that the missense mutation in the FOXP2 gene also impacts other cognitive functions.
Finally the publishing of services delivering mutation impact information in a format that can be readily integrated with other services will facilitate the reuse of mutation impacts to other communities.
Among these features, the mutation impacts are continuous attributes, and the other features are nominal attributes.
We also must transfer these findings into human cell experimental systems that allow researchers to examine the impact of the mutations or other alterations of the genome on cellular pathways and the resulting disease biology.
Mutation impacts are essential for understanding the role of mutations.
Here, we have extended the Beerenwinkel model to describe multiple classes of mutations; both deleterious and advantageous mutations, and other mutation classes that do not directly impact on a cell's fitness.
Finally, a single-residue substitution of D510A that disrupts its salt-bridge interaction with DPP4 R317, or a change of E513A that disrupts its hydrogen-bonding interaction with DPP4 Q344, also hindered, to variable degrees, both binding and viral entry; while the impact of other mutations such as R511A was not significant.
