Sentence examples for mutations identified from from inspiring English sources

With an increase in the number of disease causing genetic mutations identified from epilepsy cohorts, zebrafish are proving to be an attractive vertebrate model for functional analysis of these allele variants.

Taken together, these data show that the mutations identified from 2 CHI patients are associated with a loss-of-function of the UCP2 protein corresponding to a loss of uncoupling activity seen in yeast.

The suppressor mutations identified in this study also share overlap with mutations identified from an identical screen in the yeast PKA homolog Tpk2, demonstrating functional conservation for some residues.

The data can be separated into two sets; one set of mutations is extracted from the COSMIC database, which is filtered for mutations more likely to be causal, and the rest of the data consists of mutations identified from large-scale sequencing efforts comparing tumor samples to matched normal samples of the same individual [23], [24].

Mutations identified from previous study.

Any somatic mutations identified from this set would be false positives, as explained in a previous study [ 13].

The last mutation identified from this genetic screen, P5, is located at the end of the G α-helix and contains a leucine instead of a proline.

All samples were sequenced multiple times bidirectionally to verify the induced mutation identified from TILLING.

Each mutation identified from the reference sequence, NM_000352.3, was confirmed by resequencing the original sample.

In fact, a monogenic trait, hair ridge in Rhodesian and Thai Ridgeback dogs was mapped and the causative mutation identified from an association study with 10 cases and 10 controls.

The metalloproteinase, Zmpste24, is responsible for the sequential proteolytic cleavage of prelamin A into functional and mature lamin A. The point mutation identified from HGPS patients results in the activation of an aberrant cryptic splice site causing the deletion of a 50 amino acid region from the C-terminal end of prelamin A [ 35].