Sentence examples for mutations have very from inspiring English sources

A larger proportion of COSMIC mutations have very low B-SIFT scores, suggesting that many COSMIC mutations are functionally deleterious.

The Y766F and Y766A mutations have very little effect on the T +1)2-AP fluoresignalssignals from the majority of ternary complexes in step 2.1.

The 22 patients with and 11 without detectable SMARCAL1 mutations have very similar clinical features (Table  1; Supplementary Tables  1 and 2) and similar disease severity scores, which we calculated as previously described [ 7].

In general, organisms are well adapted to their living environments, so only a few changes lead to fitness increases and these beneficial mutations have very small effects [ 32, 34, 35, 37].

Remarkably, the A206K mutations had very little effect on the FRET span (ΔR = 0.26 and 0.25 for A206K (nd) and control (d), respectively; Figure 3).

Accordingly, under high temperatures (32°CC), the tcd10 mutation has very little effect on the associated-genes for Chl biosynthesis, photosynthesis and chloroplast development, consistent with the normal phenotype in tcd10 mutants at 32 °C.

However, several classes of is-mutations had very pronounced phenotypes.

Unlike Y766A, the conservative Y766F mutation has very little effect on the kinetics of fingers closing.

The site for Leu626Gln mutation has very high structural conservation (>80%) indicating that substitution at this site might perturb DRS structure.

It is important to point out that, while many studies attempt to characterize the DFE of mutations by statistically rejecting one type of distribution in favor of another, studies focusing on the DFE of beneficial mutations often have very little power to do this, simply because the number of beneficial mutations recovered is usually very small.

It is interesting to note when these mutations are modelled in the murine intestinal epithelium, apart from Apc loss, the other mutations alone have very minor impact on intestinal homeostasis and only yield tumours at very long latencies (Kras, Tp53, Pten).