Sentence examples for mutations have prognostic from inspiring English sources

There are a number of studies which indicate that D-loop mutations have prognostic significance.

Moreover, BRAF mutations have prognostic value in stage II and III CRC patients (Roth et al, 2010).

Our results also show that p53 mutations have prognostic value in epithelial ovarian cancer, although this was of borderline significance.

Internal tandem duplication of the fms-like tyrosine kinase-3 gene (FLT3-ITD) and nucleophosmin-1 (NPmutationsions have prognostic importance in acute myeloid leukemia (AML) patients with intermediate-risk karyotype at diagnosis, but less is known about their utility to predict outcomes at relapse.

Second, although both NPM1 and CEBPA mutations have prognostic value in NK AML and some previous study also suggested the association of NPM1 and DNMT3A mutations [ 24, 25, 27], our present study did not include the data of NPM1 and CEBPA mutation status and, therefore, comprehensive analysis in terms of mutational relations among three genes (NPM1, CEBPA, and DNMT3A) could not be performed.

We found no evidence that KRAS mutations had prognostic value, although a trend was observed in some stratifications.

Analysis of more cases and a longer period of follow-up will be necessary to determine whether this mutation has prognostic or therapeutic value.

The type of the mutation has prognostic significance, as the average age of ESRD depends on the type of the disease and amounts to 53 years in type 1, and 69 years in type 2 [ 1].

Molecular analysis of driver mutations is standard care in lung cancer in the era of personalized treatment as the presence of a driver mutation can have prognostic and predictive value-targeted therapy [ 1, 2].

However, KRAS mutation did not have prognostic value for patients with metachronous or synchronous mCRC.

However, KRAS mutation did not have prognostic value in patients with metachronous or synchronous mCRC.