Sentence examples for mutations have gained from inspiring English sources

The fitness effects of new mutations have gained significant attention both in experimental research and theoretical work [ 12, 13].

Activating EZH2 mutations have gained further attention recently because of the development of small molecule inhibitors that show a high specificity for EZH2.

However, we have shown that all tested CFC mutations have gain-of-function activity in vivo (Anastasaki et al., 2009).

This finding nicely demonstrates the potential of neutral drift mutations that have gained interest in the last decade (Bershtein et al. 2008; Bloom and Arnold 2009; Smith et al. 2011).

This result may be due to differences in the set of acquired mutations that these cells have gained following VHL loss or due to other intrinsic variations among these cells.

These cells lines may have gained additional mutations during the many passages under in vitro conditions.

In 24 out of 24 cases, they discovered that they have gained a mutation in the same gene, called FleN.

Tumorigenesis typically begins with clonal expansion of cells that have gained a set of driver mutations.

In addition to the precise histopathological diagnosis and subtyping of lung tumors which might necessitate the use of supportive immunohistochemistry the detection of possible genetic mutations, translocations, and amplifications has gained more and more importance.

Lines that had gained a mutator mutation were excluded.

Regarding evolution of AML after therapy, a recent NGS study has revealed two major patterns at relapse [ 23]; the first pattern is the persistence of a dominant clone and the second pattern is the selection and expansion of a minor clone; in both cases the relapse clone had gained additional mutations.