Sentence examples for mutations have differential from inspiring English sources

Therefore, in this study we also used the W241A mutant, which has no detectable effect on GTP binding (Fig. 2), in addition to the C277S mutant, in order to determine whether these two mutations have differential effects on the role of TG2 in cell death.

Although we did not detect a significant background-by-mutation interaction, the low P-value (0.053) suggests that the three mutations have differential effects across genetic backgrounds.

We hypothesize that infant- and adult-onset mutations have differential effects on neuronal development that could contribute to the age at which SCA13 emerges.

These results support the hypothesis that SCA13 mutations have differential effects on neuronal development that could underlie the age of disease onset.

We conclude that infant- and adult-onset SCA13 mutations have differential effects on neuronal development that could determine the age that disease emerges.

Our data further shows that synonymous and non-synonymous mutations have differential but non-significant effect on overlapping localization of orthologous genes in other insect genomes.

However, under thermal stress (42.2°C) and low glucose (DM25) conditions in the absence of rifampicin, the mutations had differential fitness effects depending on genetic background.

It is somewhat surprising that even though the Ubc9 mutation has differential effects on cells of the anterior versus posterior lobes, the overproliferation defects in both are largely rescued by ectopic expression of p21/Dap.

We showed here that GOF mutations in CgPDR1 have differential effect on transcriptional profiles.

In this study we showed that mutations in p53 have differential effects on sensitivity to TS inhibitors, which may influence response and survival after chemotherapy with TS inhibitors.

It is known that population size and mutation rate can have differential effects on the evolutionary dynamics [ 13, 40, 41].