Sentence examples for mutations has provided from inspiring English sources

The genetic study of rats and mice using natural variants, natural mutations, chemical or radiation induced mutations, engineered mutations and conditional engineered mutations has provided the tools for investigating the genetics of disease.

The discovery of these causal mutations has provided important insights into biochemical pathways involved in the etiology of Parkinson's disease.

Studies on suppressor mutations have provided the basis for identifying the 'three-letter' (codon) structure of the genetic code and they represent a formidable tool to unravel gene expression, protein structure, and function, and to understand the functional basis of mutations associated with common diseases.

Therapies targeting driver mutations have provided promising outcomes in relevant populations.

Accordingly, these mutations have provided limited information about the functional interactions of LGI1 protein.

Furthermore, several studies on the molecular and cellular consequences of disease-causing CLDN16 and CLDN19 mutations have provided critical information for the development of potential therapeutic strategies.

Furthermore, the discriminatory profiles that often contain genes located downstream of the type-specific pathogenic gene fusions or mutations have provided novel targets for molecular therapy [ 15- 18].

Gain-of-function and loss-of-function mutations have provided evidence that β-catenin plays essential roles in development and tumorigenesis.

Although these mutations have provided important insights into cardiac morphogenesis and ASD formation, in many families and individuals the causative gene is still unknown.

Both the talpid and talpid mutations have provided new insights into craniofacial ciliopathies, which can be used to elucidate the pathways and regulatory mechanisms behind ciliopathic diseases.

The development of EGFR-TKIs and the discovery of EGFR gene mutations have provided a great opportunity for translation of cancer biology into clinics to realise individualised therapies for lung cancer.