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SMN genomes are poorly characterized, and the influence of genetic background on genotoxin-induced mutations has not been examined.
Further analysis of allowing mutations has not yet taken place.
Association of BRCA1 methylation with TP53 mutations has not been shown previously.
To date, a unifying pathomechanism for all mutations has not been elucidated.
Furthermore, the distribution of pleiotropic effects of gain-of-function mutations has not been explicitly characterized.
The phenotypic heterogeneity of individuals with JBTS with the same mutations has not gone unnoticed.
Similar(28)
Furthermore, these mutations have not significantly changed the specific activities of firefly luciferases.
Moreover, oncogenic driver mutations have not been described for up to 30% of all melanomas.
However, drugs to counteract the effect of genetic mutations have not yet been found.
Naturally occurring and disease-causing activating mutations have not been identified in AT1 receptor.
These mutations have not been reported previously in the BIC or LOVD databases.
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