Sentence examples for mutations has increased from inspiring English sources

Since the first SOD1 missense mutations were reported, the number of known mutations has increased to more than 114 (see review, [4]).

Since the discovery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene [ 14- 16] the number of identified CF mutations has increased enormously.

With the significant advancements of technologies in identifying genetic predispositions, especially the next-generation sequencing technology (4 9), the number of IRD-related genes and mutations has increased dramatically to date.

Detection rates for NF2 gene mutations have increased with the introduction of newer techniques.

It is possible that people who carry HFE mutations have increased risk of CHD.

For example, glioma cells with IDH mutations have increased ROS and reduced GSH levels due to insufficient NADPH pools (Shi et al., 2015).

Kohanski et al. [34] found that a set of E. coli strains with similar mutations had increased growth in the presence of gentamycin.

Curtin and colleagues showed that primary melanomas arising from chronically sun-damages skin and mucosal sites, the latter of which typically do not harbor BRAF and NRAS mutations, have increased CCND1 copy number [26].

Viral variants that are composed of recombined genomes containing new mutations have increased the probability of altered immunogenicity.

Pancreatic cancer cells with RNF43 mutations have increased Wnt/β-catenin activity and are especially sensitive to Wnt inhibition [ 59].

Although not statistically significant due to small sample sizes, MCTs with c-KIT mutations had increased DFI and OS when treated with chemotherapy vs. surgery alone.