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The characterization of these driver gene mutations has enhanced our understanding of the mechanisms contributing to oncogenesis, allowed for improved prognostic assessment, and opened the door for the development of exciting new therapies.
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Lastly, it is theoretically possible that recent viral mutations have enhanced the virulence and transmissibility of SFTSV in humans.
Money has enhanced it, raised standards.
The DH has enhanced, not disgraced, baseball.
Seek a racquet that has enhanced maneuverability.
As response rate was not assessed in that study, the Δ32 polymorphism mutation may have enhanced tumour growth through a direct effect on tumour biology (Manes et al, 2003), resulting in the observed poor survival in these patients (Ugurel et al, 2008).
In the present case, the occurrence of the COMMD1 mutation cosegregating with the compound heterozygous ATP7B mutations appears to have enhanced Wilson disease phenotype.
We originally wished to establish whether all mutations in LRRK2 had enhanced activity towards 4E-BP, as this has been controversial for other measures of LRRK2 kinase activity.
Subjects with gain-of-function LRP5 mutations and high bone mass had enhanced lower-body fat accumulation.
Large homozygous regions have enhanced probability to harbor the causative mutation in the proband.
Mutations in these two ORFs in the genomes of 1030a, 1030c, and 1030d might have enhanced their virulence favoring their survival under stressed condition.
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CEO of Professional Science Editing for Scientists @ prosciediting.com