Sentence examples for mutations given the from inspiring English sources

The demonstration for duplications is similar and trivial for the others mutations given the definition of transitions.

The goal here was to survey changes in the codon composition caused by mutations given the genomic nucleotide composition.

P S is then the posterior probability of getting m mutations given the observed number of mutations in the IFNB and IFNK datasets.

Assuming a constant mutation spectrum across genes, we can test whether the level of site recurrence observed at each site violates the expected number of mutations given the local trinucleotide.

This, in turn, effectively reduces the probability of the occurrence of mutations, given the small population of cells at risk, despite the fact that a mutation arising in a stem cell can persist for a long time.

It should be noted however that in both the SNCA A53T and the SLC6A3 cases, the authors were not able to positively confirm the presence of de novo mutations, given the absence of parental DNA samples.

A standard multinomial likelihood model is used to describe the probability of mutation given the total number of clones sequenced and the presumed frequency of mutation.

Thus, the total probability of observing three additional individuals with truncating ASXL3 mutation, given the first de novo observation, is around 4.0 × 10-17.

VarScan2-somatic detected all the positions called by RVD2 except position 39, which turns out to be a very likely mutation given the depth distribution in Figure 6b.

In the same line, 18% of all early-onset patients (<40 years) can carry either a BRCA1 or a BRCA2 <span class="lh lhl">mutation, given the frequency of 10% found here for the four common BRCA1 mutations screened.

Yet fixation by mutation, given the low rate of mutation, is typically an absurdity that would take huge numbers of generations (e.g., this is ruled out explicitly in [ 55]).