Sentence examples for mutations give a from inspiring English sources

With reversion of the CTL mutations in the recipient, apparently some of these compensatory mutations give a fitness cost themselves, driving their reversion.

It is noteworthy that not all nd-HPFH mutations give a reproducible HPFH phenotype in transgenic mice (unpublished data).

In a recent study, Bozic et al. [ 130] provided an equation for the proportion of expected passenger mutations versus the proportion of the drivers and estimated that driver mutations give an average fitness advantage of 0.4%%.

Jessica Queller's article about BRCA mutations gives a compelling look into the quandaries faced by women who are (or might be) carriers of these genetic predispositions to breast cancer.

Here we present a modified version of SIFT called Bi-directional SIFT (B-SIFT) which is able to identify both deleterious and a subset of activating mutations given a protein sequence and a query mutation within that sequence.

All individuals tested for BRCA1/2 mutations gave a signed informed consent.

A number of mutations gave increased thermostability and a combination of six of these mutations gave a protein with an increase in Tm of 21 °C.

The current distribution of 161 non-intronic mutations gave a frequency of 13 non-intronic mutations/100 residues.

The reconstruction involved 3,955 point mutations, giving an estimate of the overall per site r/m (the ratio of base substitutions introduced by recombination relative to point mutations) of 14.9; this compares with a typical range from around 0.1 to more than 30 for common pneumococcal lineages [ 36, 37].

It turns out that quite a wide range of landscapes satisfy the condition (at least trivially) under point mutation given a sufficiently low mutation rate, while the property appears to be difficult to satisfy under genetic recombination.

A mutation gives a person about a 60percentt chance of getting the disease.