Sentence examples for mutations generated by from inspiring English sources
While they resolved some of the previous limitations from TP53 studies (mostly by examining large portions of the human genome which are usually not under selection and which have a nucleotide context that is representative of the whole human genome) they still did not address the important issue of examining mixtures of mutations generated by different mutational processes.
In a more detailed analysis of one simulation, it was shown that only 0.01% of the mutations generated by a population over 10,000 generations can go to fixation as a consequence of their improved fitness.
Altogether, data on duplication-inferred mutations generated by our approach both enriches the available pool of known mutational events within recent mammalian evolution and complements the data on disease mutations and SNPs for a contextual DNA sequence analysis of single nucleotide substitutions in humans.
In this study we provided evidences of direct correspondence by line between warnings issued by FindBugs and mutations generated by μJava mutation operators.
In this paper, we report an approach that makes use of information obtained through the application of FindBugs (Hovemeyer and Pugh 2004) on detecting mutations generated by μJava (Ma et al. 2005).
By this approach we have increased the half-life of denaturation by 300-fold compared to the wild-type Bacillus subtilis lipase through three point mutations generated by only two cycles of error-prone PCR.
The Nanog null mutation generated by homologous recombination has been described previously (Mitsui et al., 2003).
Toward this end, the present study characterised a mutation generated by insertion of the U3Neo gene trap retrovirus into an intron of the hnRNP A2/B1 gene.
Fibrillin-1 has also been manipulated in another mouse model by creation of heterozygous mice expressing a mutation generated by substitution of Cys→Gly at position 1039 C1039GG), and these mice also exhibit aortic dilatation [ 12].
We used two independent alleles of Wwox for these analyses; Wwox, a null mutation generated by homologous recombination, and Wwox f04545, which carries a pBac insertion in exon 2 (29, 29).
In Drosophila spp. recombination rates are positively correlated with nucleotide diversity [ 49- 51], especially at a fine-scale [ 51], although the relative roles of selection and mutation generated by recombination in underpinning the pattern are controversial [ 49- 51].
