Sentence examples for mutations from subsequent from inspiring English sources

We, therefore, removed these mutations from subsequent analyses.

Our findings provide reassurance that, at least from an mtDNA perspective, methods currently under development have the potential to effectively eradicate pathogenic mtDNA mutations from subsequent generations.

It is obvious that the development of targeted cancer therapies resulted from profound understanding of oncogenic driver mutations and from subsequent application of selective inhibitors such as the tyrosine kinase inhibitor Imatinib targeting the genomically modified abl-kinase or gain-of-function mutations in c-KIT.

However, L188V is a Type 2C mutation and G104V, V130I and Y175C have been described as germline mutations associated with PCC; these mutations were excluded from subsequent analyses.

Furthermore, drug resistance, arising from a subpopulation of original tumor cells or from subsequent mutations under the selection pressure of drug treatment, has been a major hurdle in cancer treatment.

An additional 23 mutations were reported at 100% allele frequency in all 10 libraries, and were identical in each of the ten libraries; these were excluded from subsequent analysis as mutations that were evidently present in the parent strain prior to mutagenesis.

It turns out that subsequent analysis of mutations from different α values also leads to a relatively small difference.

In total, mapping was attempted for 486 mutations from the Tübingen I screen and subsequent screens of the mutant collection and successful for 389, giving a success rate of 80%%. 12 of these could be mapped only with the H2 set.

The mutation would survive in the population because it would protect carriers from subsequent outbreaks of plague.

The data from patient 2 also support the extensive clonal spread of mtDNA mutations and subsequent tumor development after acquiring sufficient mtDNA and/or nDNA changes.

Consequently, they were removed from subsequent analysis.