Sentence examples for mutations from our from inspiring English sources

"If we inherit mDNA with mutations from our mother, we age more quickly".

We excluded these parental mutations from our analysis.

In order to not exclude any potentially important escape mutations from our figures, we ran the analysis with and without the covariation correction, and included all HLA-associated polymorphisms identified by either method in the escape maps.

Thus, we concluded that nonsynonymous nucleotide substitutions in these codons are likely caused by random mutational process after integration of mtAncestor-2 into the nuclear genome and excluded these mutations from our analysis.

Three of the nine mutations from our cohort were novel (Ile730Asn, Asp717Gly and Arg719Pro).

(D ) 62 patient-derived PTEN phosphatase domain missense mutations from our in-house endometrial cancer data set and TCGA were mapped onto the surface of PTEN.

In addition we included 16 index patients with known pathogenic point mutation from our population in the array CGH analysis.

Indeed, the similarities with FBC extend to the types and positions of mutations in MBC in PIK3CA with the frequencies of exon 20 mutations>exon 9 mutations>exon 5 mutations (aside from our previously reported E547K PIK3CA mutation (Deb et al, 2012a), which is rarely seen in FBC), and interestingly, the only gene mutation noted in more than one TCGA MBC sample was PIK3CA (two H1047R, one E545K).

Of the 3994 mutations identified from our screens, 3799 (95.12%) resulted from mutation of a guanine and only 195 (4.88%) from mutation of an adenine, consistent with the preference for guanine adduct formation.

Eighteen deleterious mutations identified from our cases reside in actionable genes (Table 3), although their impact is still unclear for many.

The GCK261 mutation carriers from our family, like those from the EMCD, had a significantly higher glucose and insulin response compared with GCKm carriers (Table 1).