Sentence examples for mutations from a from inspiring English sources

In the present study, we used directed evolution to identify specific amino acid mutations from a pool of randomly mutated variants that enhance the stability of the protein fold.

We verified the new method with precisely discovering three most important EGFR drug-related mutations from a sample in which EGFR-mutated cells only account for a small percentage of whole cell population.

B2 present in two samples from Ammersee (Danube catchment) was a notable exception, because it was separated by two mutational steps from B and by three mutations from A, and thus represented an intermediate haplotype.

In order to collect experimentally verified LoF and GoF mutational information, we obtained 816 LoF mutations and 474 GoF mutations from a literature text-mining process.

L can be interpreted as the mutational target size of selection, or more generally the number of possible beneficial mutations from a given starting genotype.

Without doubt, base substitution bias will diverge the distribution of mutations from a Poisson distribution, effectively diminishing the functional size of a randomly mutated gene library available for subsequent screening [ 9].

Most people think of inbreeding as bad, but it could be helpful in purging deleterious mutations from a population".

Studies of the relatives of A-T patients have consistently suggested that they are at increased risk of breast cancer [ 6]. Thompson et al. [ 7] estimated the risk in heterozygous carriers of A-T-causing mutations from A-T case families to be 2.23 times higher (95% confidence interval [CI] = 1.16-4.28) that that of the general population.

Let the null mutation rate, or the rate of mutation from A to a, be u per gene per generation.

This study compared clinical and radiological characteristics of MED caused by MATN3 mutations versus COMP mutations, from an orthopaedic point of view.

We have used this approach to successfully map a collection of mutations from an ethyl methanesulfonate−based mutagenesis screen on the third chromosome.