Sentence examples for mutations frequency in from inspiring English sources
The present study was designed to detect and characterize K-ras mutations in azoxymethane (AOM -induced AOM -inducedpt foci (aberrantmicryptnd determine whether dietary supplementation ofocilenium influences K-rACFmutatinns frequency in ACF using a new PCR technique of locked nucleic acid-miceanddetermineme PCR clamping combined whethertant-specific probes.
The CODDLE application http://www.proweb.org/coddle/ is useful to evaluate truncation mutations frequency in the gene sequence; however we found that a more accurate selection of the fragments can be performed by manual sequence analysis.
Mutations frequencies in KRAS, BRAF, PIK3CA, PTEN, and TP53 were found to be within previously reported range supporting the representativeness of the series [38].
In our experiments described below (see next Section and Section "Different mutations frequencies in other genes") in 31 sequenced GPR14 clones no mutations were found indicating that this mutation is rather rare.
We found significant mutation frequency in a number of genes previously known to be somatically mutated in colon cancer patients including APC, TP53 and KRAS.
We attempted to develop a therapeutic that would inhibit the CEES-induced increase in mutation frequency in the skin.
We identified alterations in DNA copy number and complex genomic rearrangements and demonstrated a low somatic point mutation frequency in the absence of tobacco mutagens.
The overall c-kit mutation frequency in exons 8, 9, 11, 13, 15 and 17 was determined to be 25.86% (15/58).
We next investigated whether overexpression of the hPolλ W438 variant could affect mutation frequency in vivo.
In the duodenum and the jejunum, but not in the more distal ileum, we see the significantly higher mutation frequency in mucosa as compared to the serosa.
We found that, similar to a previous report [29], nutrient depletion induced a chronological-age-dependent increase in mutation frequency in wild-type cells (Fig. 5D; "vector").
