Sentence examples for mutations for single from inspiring English sources

The first is that although some mutations for single gene disorders may be included in the test, the company may not include all potential mutations (Cornel et al. 2014), or even those that are most relevant for the particular population to which the consumer belongs.

Deletion mutations for single chromosomes were treated separately.

Moreover, frequency of spontaneous mutations for single and combined antibiotics were also evaluated.

When all known mutations can be detected, we set the threshold for minimum and maximum read percentage with non-reference nucleotide to detect new mutations for single copy genes.

The mutations rates for single nucleotide changes have been reported in B. anthracis based upon selection for antibiotic resistance (Rif) and are very similar to the rates observed for other well-studied bacteria (2).

It has been estimated that there is about 1000 point mutations for every single deleted mtDNA molecule in mtDNA mutator mice (if there is >0.02 deletion per mtDNA molecule) [ 22].

Alternatively, there may exist a spectrum of distinct possible resistance mutations for a single drug, each conferring a different response to therapy (Sierra et al. 2010; Xu et al. 2012).

If resistance to different drugs is conferred by different mutations, then the likelihood of a patient having cancer cells with the multiple mutations required for resistance to combination therapy should be smaller than the likelihood of having the mutation required for single agent resistance.

Given that CNV-formation rate is considerably higher than the mutation rate for single base pairs [27], it is advisable to create population-specific priors to account for varying degrees of genetic diversity.

In addition, there are many databases that store and serve somatic mutation data for single genes (see http://www.hgvs.org for an extensive list).

As it is important to identify single crypt level mutations to understand UC-associated tumorigenesis, we surveyed the whole coding region of p53 for mutations of single crypts within lesions, using our novel method of microdissection from serial histologic sections (Yoshida et al, 2003).