Sentence examples for mutations for instance from inspiring English sources

Other mutations, for instance, the pathogenic TPI variants Gly122Arg or Val154Met could not be assigned to defined domains.

As a first step in developing an antibiotic-sensitive live recombinant E. ictaluri vaccine strain (RAEV), we adapted suicide vector technology [27] to E. ictaluri to construct defined unmarked chromosomal deletion mutations, for instance the asd deletion.

So long as neutral changes are much less likely than beneficial ones, repeatability is not greatly affected – under truncating selection, assuming that neutral mutations are 1% as likely as favored mutations (for instance when Nes = 50) reduces repeatability by around 5% either allowing (7.8% to 7.4%) or not allowing (7.1% to 6.7%) back mutations.

Synonymous mutations, for instance, are less constrained comparing to non-synonymous mutations.

The intra-molecular structures contain compensatory mutations, for instance, between alignment positions 60 and 65.

This copying activity has been linked to a range of deleterious mutations, for instance chromosomal aberrations, and faulty expression of genes [ 1].

In this work, we applied all mutation operators supported by Milu, that are divided in four categories: statement mutations, operator mutations, variable mutations, and constant mutations, including, for instance, the classical operators of arithmetic and logical operators replacement.

De Grey's fix for mitochondrial mutation, for instance, is to smuggle backup copies of DNA from the mitochondria into the vault of the nucleus, which evolution annoyingly failed to do — probably because the proteins needed in the mitochondria would ball up during their journey through the watery cell body.

On the other hand, massive reduction in intron number could reflect "runaway" mutation, for instance due to elevated rates of creation of intronless DNA copies of genes by widespread retroposition associated with retroelement invasion (Roy and Penny 2007).

Additionally, the ubiquitous export factor GLE1 may have tissue-specific effects contributing to the phenotype caused by the dominant p.R584W mutation; for instance, if it only affects the transport of a specific subset of messenger RNAs or if particular tissues are more sensitive to the temporospatial regulation of gene expression (Hurt and Silver, 2008).

Sun-exposure is an etiological factor in MCC, as evidenced by the finding of UV-related mutations in for instance TP53 in MCC, and clinical association of MCC with other non-melanoma skin cancers [23], [24].