Sentence examples for mutations for further from inspiring English sources

14813 mutations across 4052 protein sequences received both a B-SIFT score and a SNAP prediction, and so we focused on these mutations for further analysis.

This focus helps to reduce the number of mutations for further investigation.

We thus established two HBx constructs containing these two representative mutations for further experiments.

Given their uncertain pathogenic potential, both variants were discarded as mutations for further calculations.

Computer-aided annotation enables research groups to filter and prioritize potential disease-causing mutations for further analysis.

In these scenarios, we believe that SNAP can generate a rank order of mutations for further study.

To fix desirable Ig mutants by stopping hypermutation or to resume mutation for further improvement of Ab affinity, activation-induced cytidine deaminase (AID), a key enzyme responsible for the Ig mutation machinery, must be switched on or off.

Thus, it was decided to concentrate our efforts on the T315I mutation for further analysis.

To identify a subset of mutations suitable for further attenuation of W1806, we analyzed effects of E138K and K279M changes on virulence, growth properties, and immunogenicity of derivatized W956, from which chimeric W1806 inherited its biological properties and attenuation profile.

Mutations chosen for further structural analysis had either B-SIFT score greater than 0.5 or both a positive B-SIFT score and cancer-specific overexpression with a one-tailed t-test p-value less than 0.001.

Because mutations associated with node removal are likely to generate incomplete fragments or nonfunctional gene products (Zhong et al. 2009; Wang et al. 2012), we emphasized only on edgetic perturbation (due to deleterious mutations) model for further investigations.