Sentence examples for mutations expression of from inspiring English sources
To confirm that disruption of Rv0431 caused the altered immune responses in macrophages, and to rule out effects due to secondary mutations, expression of Rv0431 was restored in Tn Rv0431 by complementation using the predicted promoter upstream of Rv0430.
We searched for microsatellite instability (MSI), presence of hMSH2 and hMLH1 germline mutations, expression of hMSH2, hMLH1 and p53 proteins in tumoural tissue samples by immunostaining.
Analyses of hyperplastic synovial tissues of patients with RA reveal features of transformed long-living cells such as the presence of somatic mutations, expression of oncogenes, and resistance to apoptosis [ 1- 3].
In primary breast cancers lacking p53 mutation, expression of both ASPP1 and ASPP2 was reduced.
Recent work identified several genes required for the BRAFV600E-induced senescence and showed that in the context of BRAF mutation, expression loss of one of them, IGFBP7, is critical in promoting the progression to melanoma [23].
The development of quinolone resistance needs only two mutations, e.g., expression of inducible cephalosporin-resistance in Enterobacter spp. [16].
In addition, identification of the mutations affecting expression of the flagellar gene fljB can be useful to support the monophasic character observed phenotypically.
Even though the ligand-binding function was abolished by these two mutations, the expression of these mutants was normal at the protein level.
In order to identify additional molecular changes associated with the presence of β-galactosidase mutations, the expression of canine lysosomal multienzyme complex components in GLB1+/+, GLB1+/− and GLB1−/− fibroblasts was investigated by quantitative RT-PCR, Western blot and enzymatic assays.
The subgenomic promoter was inactivated with 13 synonymous mutations and expression of the EEEV structural proteins was placed under the control of an internal ribosomal entry site (IRES) derived from encephalomyocarditis virus (EMCV).
Intriguingly, any of several maternally inherited ICR mutations affected expression of the paternal AK029869 transcript in trans.
