Sentence examples for mutations express the from inspiring English sources

Some Wilms tumours with WT1 mutations express the mutant RNA and protein (27).

It is intriguing that TGF β1 treatment of the NR4 hepatocyte cell line increased the expression of α1 integrin subunit mRNA (Serra et al, 1994), directly correlating with our findings that cell lines with TGF β1-activating SMAD4 mutations express the α1 β1 integrin.

There was a perfect concordance between the type of mutation and p53 expression as every missense mutation expressed the protein, while the two stop mutations did not.

There was no difference in age between the two groups (total mean, 43.5 ± 5.5 years) nor in the estimated glomerular filtration rate (total mean, 91.1 ± 14.9 mL/minute), and all patients had a described mutation expressing the classic FD phenotype with severe multiorgan involvement, which makes unlikely the hypothesis that they had a stable or a slowly progressing disease.

In a recent paper by Geibel et al., the authors report photocurrents for the triple mutant (as well as the respective single mutations) expressed in the oocyte expression system.

Transgenic line H L44,H R388 carried one copy each of transgenes encoding S44L and K388R human Spastin mutations, expressed via the inducible geneswitch elav-GAL4 driver (Osterwalder et al., 2001), in the spastin 5.75 null background.

This fact is interpreted as different opportunities for selection against deleterious mutations among fitness components because deleterious mutations expressed at the early life-cycle stages are more frequently purged from inbred populations than those at late life-cycle stages (Husband and Schemske, 1996).

Full-length genomic clones bearing these mutations, expressed using the endogenous promoters and containing their complete intron-exon structures, were fused at the C-terminus to a FLAG peptide epitope tag, as were equivalent wild-type (non-mutant) constructs.

As deduced from transcript profiling with microarrays, a high number of genes (up to 385) were differentially regulated by a selected number (7) of GOF mutations expressed in the same genetic background.

We know now that mutation penetrance (the percentage of subjects bearing a mutation who express the phenotype) is highly variable and may be substantially delayed or incomplete.

The traits are not learned, because individuals that have the neutral, intermediate mutation will always express the beneficial phenotypic mutation at a low rate.