Sentence examples similar to mutations explained by from inspiring English sources

In Norwegian White Sheep (NWS), two myostatin (MSTN) mutations affecting conformation and fat classes are segregating: the 3'-UTR mutation creating an illegitimate microRNA site (c.2360G>A) that was identified in Texel sheep [ 1] and a frameshift mutation explained by a deletion of one base pair in nucleotide position 960 (c.960delG), identified in NWS [ 2].

(A ) The fraction of (log) viral fitness variation explained by deleterious mutations over time for the simulation whose phylogenies are plotted in Figure 6.

This extreme haplotype heterogeneity indicates that R116W is a recurrent mutation, maybe explained by the high mutability of CpG dinucleotides.

Relatively often, a novel mutation is explained by a local DNA sequence change, affecting one or a few adjacent nucleotides.

The greater severity of the T158M mutation is explained by more extreme destabilization of the protein, coupled with reduced affinity for modified DNA.

Such a pattern of changes that involves multiple mutations could be explained by an initial deleterious mutation compensated by selection on subsequent mutations that restored the identity of the S residue.

However, most of the increase in their mutation rates is explained by the high mutation bias of the {C > G | 1, CG} context itself.

This paucity of new mutations may be explained by the presence of standing variation in the ancestral populations, which likely provided a rich pool of alleles for selection to act upon immediately.

Such mutations can be explained by at least two mechanisms: (1) independent mutational events occurring in individual cells; and (2) linked mutational events arising from clonal outgrowth of a single cell containing the microsatellite mutation.

How can an overall decrease in γ-secretase activity caused by PSEN mutations explain the observed increase in the Aβ42/Aβ40 ratio?

(b) PD14713a is haploid on chromosome 5q, so the mutual exclusivity of APC mutations cannot be explained by occurrence in different chromosome copies.