Sentence examples for mutations experience from inspiring English sources

Patients who have such mutations experience night blindness, loss of their peripheral visual field, and loss of central vision [1].

Patients with CFB mutations experience ongoing activation of the alternative pathway and usually have very low C3 levels.

Although 80% of lung cancer patients who are carriers of EGFR TK domain mutations experience partial responses or marked clinical improvement with gefitinib or erlotinib, patients without such mutations are refractory to these agents (Lynch et al, 2004).

The Raman results show that colon cancer cells experience a large spectral response to erlotinib, but colon cancer cells expressing oncogenic BRAF or KRAS mutations experience small or no relevant effects, respectively.

We also analyzed the relapse patterns after CRT and found that patients with KRAS mutations experience early distant relapses, especially in the brain, more frequently than patients with wild-type KRAS.

Owing to the absence of a control group, inference of treatment effects may be confounded and it remains uncertain whether all patients would respond to eculizumab or even require treatment as reports indicate that some patients with aHUS, for example, those with CD46 mutations, experience natural recovery without any therapy.

No patients without known BRCA mutations experienced objective anti-tumor responses.

In the present study, women with germline mutations experienced a risk for metachronous ipsilateral breast cancer that was not significantly different from that in women without mutations.

The ratio between the number of beneficial and deleterious mutations experienced by a population of RNA sequences increases with the value of the mutation rate μ at which evolution proceeds.

In this study, 2/49 (4.1%) patients whose isolates did not have apparent rpoB gene mutations, experienced treatment failure compared with 3/3 (100%) patients whose isolates did have rpoB gene mutations and were deemed rifampicin susceptible with phenotypic methods.

Similarly, Shigaki and colleagues found in a series of 219 patients who had undergone curative resection of stage I III esophageal squamous cell carcinoma that patients with PIK3CA mutations experienced significantly longer DFS, CSS, and OS than those with wild-type PIK3CA 49.