Sentence examples for mutations existing in from inspiring English sources

More interestingly, the mutations existing in target gene are easily observed by the naked eye.

The dystrophin gene is evolutionarily well conserved and a number of animal models of DMD have been described including mouse (mdx) [33], [34], dog (GRMD) [35], zebra fish [36], C. elegans [37] and Drosophila melanogaster (dmDys) [15], [38], [39], [40], [41], [42] with mutations existing in the dystrophin gene in vertebrates or invertebrates genes [15], [43].

For mutations present in dbSNP (which are usually germline mutations), we removed potential germline mutations existing in database of dbSNP132 for the downstream analysis.

It seems that autophagy function depends on several factors, for example, step of tumor formation, tissue origin, and gene mutations existing in specific cancer type.

Numerous studies have suggested that the expression and activity of many protein kinases and phosphatases can be influenced by single nucleotide polymorphisms (SNPs) or rare point mutations existing in human genomes.

This shortcoming of the asexual reproduction was first realized by G. Muller and was finally formulated as "ratchet" [ 90]: "an asexual population incorporates a kind of ratchet mechanism, such as it can never contain, in any of its lines, a load of mutation smaller than that already existing in its at present least-loaded lines".

We suppose that in the past this gene existed without insertion of the nucleotide t in position 841 (towards first nucleotide of a gene) and mutations could not blur the TP existing in this region (Fig.  5).

However, there are still some inconveniences and weaknesses in DE algorithm, such as the inconveniences in the choice of proper control parameters and the defects existing in a given mutation strategy.

Additionally, mutations in existing introns may engender compensatory mutations or activation of latent splice sites altering the lengths of associated intronic and exonic sequences (Gan et al. 2011; Long et al. 2013).

49 These experiments clearly confirm that point mutations in existing β-lactamases can result in the selection of resistant mutants, ostensibly the result of reduced β-lactamase affinity to avibactam.

The resulting AncesTree algorithm is better able to identify ancestral relationships between individual mutations than existing approaches, particularly in ultra-deep sequencing data when high read counts for mutations yield high confidence VAFs.