Sentence examples for mutations except the from inspiring English sources

The qualitative step (melting curves) detected all the mutations except the T237S homozygous genotype which was only detected after equimolar mixing with a wild type sample using the HRM method alone (not shown).

In this study, we found that all the hβ2 mutations except the mutation 4K4R largely shared most of kinetic characteristics in activation, inactivation and recovery with the wild-type hβ2 subunits, suggesting that the net charge rather than the structural change confers the nonlinearity on instantaneous I-V curves.

They were all novel mtDNA mutations except the one at np 152 of G12 (Liu et al, 2001).

Consistently with these data, whole genome sequencing of in vitro selected mutants identified only few mutations except the upstream and coding regions of fabI, with the promoter mutation as the most probable cause of fabI overexpression.

All mutations except the nonsense mutation p.Gln234X (c.700C > T) (only conserved in the Gorilla gorilla and RFVT1) and the p.Ala284Asp (c.851C > A) mutation (not conserved in Danio rerio) alter amino acids evolutionarily conserved from humans to D. rerio and are also conserved in RFVT1 and RFVT3 (Fig. 2B).

As observed already with the recombinant heterotrimer containing the truncated β subunit, all of the mutations except K126A reduced the total activity in the absence of glycogen, albeit to varying extents.

Mutagenesis with multiple sets of primers was performed using the same protocol as for single site mutations, except for the presence of more than one primer set in each tube.

However the forces that act on de novo mutations are the same as we have modelled for segregating mutations, except that the allele frequency for de novo mutations is very low.

SMs were characterized by chromosomal rearrangements resulting in activated kinase signaling in 40%, and an absence of TERT-p mutations, except for the one SM that succumbed to hematogenous metastasis.

Second generation TKI can overcome certain TKI-resistant mutations except for the pan-resistant T315I.

Without any mutant DNA enrichment before the IDH1/2-specific PCR, the test showed high analytical sensitivity with detection of mutant allele frequency, ranging from 0.6% for IDH2 R172K to below 5% for all mutations except for the rare IDH2 R172S one.