Sentence examples for mutations even if from inspiring English sources

In this way, the proper functioning of Hsp90, and other chaperones, may buffer phenotypic expression of mutations even if the chaperones do not physically interact with the mutated proteins.

The high-risk group includes women who are prone to breast cancer because they have certain genetic mutations, BRCA1 or BRCA2, or those whose mothers, sisters or daughters carry those mutations, even if the woman herself has not been tested.

However, part of the mutation produced by transposable elements might affect genes useless in laboratory conditions and will therefore be taken into account in the calculation of mean fitness effects of mutations even if they do not affect any phenotype in the laboratory environment.

Are we allowed to think that progressive evolution causally related to the harmful mutations even if they are prerequisites for their overcoming by subsequent evolution?

Current technologies are sensitive enough to detect tumor-specific somatic mutations, even if the ctDNA fragments represent only a minority of all DNA fragments in the circulation.

Current NGS technologies are sensitive enough to detect tumor-specific somatic mutations, even if the ctDNA fragments represent only a minority of all DNA fragments in the circulation.

Buffering mechanisms that protect against those various kinds of perturbations have the consequence of reducing the sensitivity of the organism to an inherited mutation, even if the original buffering mechanism arose to protect against environmental or developmental perturbations.

In these settings, a substantial decrease in ΔCT between the pre- and post-treatment samples for an individual could indicate the emergence of a mutation even if the ΔCT does not drop below the cut-off established for screening.

This work could be extended to properly identify the gene associated to a mutation, even if it appears in the caption of the table, in a column header, and/or as a field in the same row as the mutation.

In fact, other genes of relevance to cleft palate development, like IRF6, were also found to be affected in mice with the p63-SAM mutation, even if to a lesser extent than FGFRs.

Given the proven sensitivity of our techniques we would therefore have expected to detect the hypersensitive ER-α mutation even if present in only a minority of cancer cells or contaminating normal cells.