Sentence examples for mutations encode for from inspiring English sources

Most frameshift mutations encode for truncated proteins of lower molecular weight with a mutated C-terminus (Table 3).

These exon 6 mutations encode for a truncated protein that displays elevated expression and activity due to loss of a C-terminal degradation domain.

Thus, studies are required to confirm whether individuals with gene mutations encoding for mutant NOD2 proteins are predisposed to MTB-infection.

The patient also tested negative for gene mutations encoding for complement factors H, I and B as well as C3, membrane cofactor protein, complement factor H-related protein 5, thrombomodulin, diacylglycerol kinase-epsilon, plasminogen and ADAMTS13.

To overcome the natural variability associated with patient-derived cell lines, we asked if we could recapitulate the sensitivity to ionizing radiation by introducing the RAD50 c.1114C>T mutation encoding for RAD50-Q372X inthethendogenousus locus of an immortalized human colon cancer cell line HCT116 (Figure 2c).

The p.Cys615X mutation encodes for a truncated protein that lacks the last 51 amino acids in its carboxyl-terminal tail.

In sanroque mice, an Rc3h1 missense point mutation, encoding for a Met to Arg substitution translates into a minor conformational shift in the RNA-binding ROQ domain (Srivastava et al., 2015) of ROQUIN and a loss of function in post-transcriptional repression.

Passenger mutations encode target melanoma antigens for human cancer immunotherapy.

Ras mutations which encode for constitutively activated proteins are found in 30% of human cancers.

K-Ras mutations that encode for activated proteins are found in more than 90% of all pancreatic cancers (Jaffee et al, 2002; Shore et al, 2003).

CDG is a collection of rare, under-diagnosed genetic disorders with gene mutations encoding enzymes necessary for protein N-glycosylation.