Sentence examples for mutations during the from inspiring English sources

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Recombination could contribute to this mutational effect, because recombination can cause mutations during the resolution of double-strand breaks [ 43].

Neurospora detects duplicated copies of sequences in the genome and mutates both sequences by repeated point mutations during the sexual cycle [ 45].

The main consequence of the mitochondrial proof-reading deficiency in mtDNA mutator mice is the progressive, random accumulation of mtDNA mutations during the course of mitochondrial biogenesis.

A comparable outcome was achieved between the patients with or without emergence of LMV-resistant mutations during the ETV treatment.

Recently, it has been demonstrated that somaclonal variations result from newly induced mutations during the tissue culture process and not pre-exist in the plants before being cultured (Sato et al. 2011).

Hepatitis B virus (HBV) infection is a major global health problem and many studies have underlined the importance of inter individual variability and somatic mutations during the clinical course of HBV infection.

Mutations during the duplication process enable populations to evolve and adapt.

The age-dependent decline in the capacity of mitochondria to dispose of these oxy-radicals renders mtDNA more vulnerable to mutations during the ageing process [28].

The decrease of performance for models that predict change in VL (CD4+ T-cell count) for time points after 180 (360) days might be explained by the emergence of new mutations during the course of therapy.

Historically, it has been known that stable L-forms are genetically different from their parent strain due to accumulation of mutations during the lengthy process of their selection, although the mutations involved remain poorly characterized [5], [17].

We therefore propose that a defective FA/BRCA pathway may contribute to the genomic instability of CML cells, thus promoting the accumulation of mutations during the progress from a chronic phase towards blast crisis.

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