Sentence examples for mutations directly in from inspiring English sources

Thus far, oncogenic viruses have not been shown to induce DNA mutations directly in human cells; rather, their contribution seems to lie in promoting and hastening the process of mutation.

This report has described a convenient genotyping method capable of detecting point mutations directly in human genomic DNA based on the combination of ligase chain reaction (LCR) and microbead-enrichment technique.

HCA not only proved to be a powerful tool to understand the functional abnormalities of AR mutations directly in patient-derived specimens, but was also utilized to predict clinical responses to a variety of experimental treatments.

Only mutations directly in the donor and acceptor sites were considered.

Instead of characterizing function in model systems, exome sequencing potentially allows for evaluating the functional consequence of pathogenic mutations directly in humans.

Several investigators have used in-house molecular tests to detect azole resistance mutations directly in patient samples, using both tissue and respiratory secretions [ 46, 47].

The method provides a convenient and simple strategy to detect point mutation directly in human genome.

Adequate methods for monitoring any type of gametic mutation directly in man are virtually nonexistent.

Surprisingly, the S205V mutation, directly in the proton wire of avGFP, does not eliminate ESPT, but slows it by up to 30-fold.

A mutation directly in the active site would result in a larger, more disruptive change (e.g., even a single additional carbon center would fill an additional 4 Å radius) and therefore be unable to provide the necessary fine-tuning.

Moreover, PCR/RFLP was a rapid and accurate method for the detection of clarithromycin resistance through a gene mutation directly in gastric biospsy samples and can be used together with histology to decide for prescription of clarithromycin containing regimen therapy.