Sentence examples for mutations derived from from inspiring English sources
Somatic mutations have a critical function in cancer pathogenesis, and mutations derived from haematopoietic stem cells and progenitor cells have also been detected in peripheral-blood cells.
UMS is an in-silico scan to evaluate the destabilizing effects of multiple point mutations derived from the protein atomic model.
Identification of PTPRS by a hybrid analysis of global gene expression (Afffymetrix) and observed DNA mutations derived from targeted exome nextgen DNA sequencing of 1321 genes.
Toward this goal, a third step of site-directed mutagenesis (named III) was applied to combine mutations derived from different CK1 and CK2 lineage-derived clones.
CR4/5 mutations derived from patients with telomere biology disorders provoke defects in catalysis and TERT binding similar to TCAB1 inactivation.
With caveats, computational prediction of stability can be used to guide mutation, and mutations derived from consensus sequence analysis, especially improved by recent co-variation filters, are very likely to stabilize without sacrificing function.
These naturally occurring mutations derive from germline and somatic origins.
Isaka, K. et al. Establishment of a new human cell line (EN) with TP53 mutation derived from endometrial carcinoma.
HNIL(H143), harboring a type-2 el1 mutation derived from the 'H143' cultivar, shows an early-flowering phenotype only in long days, but not in short days, compared with the HNIL(M23), which has a functional EL1 allele derived from the 'Milyang23 (M23)' cultivar (Kwon et al. 2014).
Receptor occupancy is dramatically reduced in the fasted state and in a receptor carrying a mutation derived from patients with Maturity Onset Diabetes of the Young 1 (MODY1).
One of these clones had one nucleotide polymorphism in the sequence overlapping with one of the primers used for amplification (mutation derived from the primer and not the cloning strategy), one clone had a PCR-induced mutation, and two clones had the correct sequence.
