Sentence examples for mutations derive from from inspiring English sources

These naturally occurring mutations derive from germline and somatic origins.

CR4/5 mutations derived from patients with telomere biology disorders provoke defects in catalysis and TERT binding similar to TCAB1 inactivation.

Somatic mutations have a critical function in cancer pathogenesis, and mutations derived from haematopoietic stem cells and progenitor cells have also been detected in peripheral-blood cells.

Toward this goal, a third step of site-directed mutagenesis (named III) was applied to combine mutations derived from different CK1 and CK2 lineage-derived clones.

UMS is an in-silico scan to evaluate the destabilizing effects of multiple point mutations derived from the protein atomic model.

Identification of PTPRS by a hybrid analysis of global gene expression (Afffymetrix) and observed DNA mutations derived from targeted exome nextgen DNA sequencing of 1321 genes.

With caveats, computational prediction of stability can be used to guide mutation, and mutations derived from consensus sequence analysis, especially improved by recent co-variation filters, are very likely to stabilize without sacrificing function.

We successfully applied this method to detect 12 point mutations derived from human p53 gene.

Then, throughout the fifties, a few other movies addressed the problem of nuclear destruction directly while horror films raised similar problems in the themes of alien invasions or human mutations derived from uncontrolled radioactivity.

Most 21OHD patients are carriers of deletions of the gene encoding 21OH, CYP21A2, or of any of the 9 most frequent point mutations derived from the non-functional CYP21A1P pseudogene.

Moreover, the protocol is based on assembly of PCR products rather than of sequenced inserts in plasmids, which means that a portion of the constructs obtained will contain mutations derived from the primers or the PCR amplification.