Sentence examples for mutations currently known from inspiring English sources

Of the 64 mutations currently known for the regulatory protease CFI (Supplementary Table S1), 49 were missense mutations, six were nonsense, two were deletions, one was silent, one was a frameshift, two were insertions and one was a splicing event.

It is conceivable that more mutations or associated mutations than currently known are involved in the development of drug resistance and lead to therapeutic failure [ 5].

However, mutations in currently known breast cancer predisposition genes are very rare, and the majority of women who undergo genetic testing for these genes are not found to be carriers of mutations (identifiable by current molecular methods).

The causes and timing of the mutations are not currently known.

Most mutations that are currently known were discovered by tracing their effects through families.

Some articles have predicted that as additional or secondary mutations, novel mutations combined with those currently known are involved in NNRTIs resistance by directly increasing resistant level of RT inhibitors or compensating the loss of replication capacity [ 8].

Mutations contributing to cancer pathophysiology are termed driver mutations whereas those not currently known to contribute are termed passenger mutations.

These data confirm recent studies showing that COMP mutations are the predominant cause of MED [Zankl et al., 2007], while type IX collagen gene mutations account for only about 10% of the currently known mutations in AD-MED.

Since the LCA chip did not contain CEP290 variants at the onset of this study, only a fraction of currently known mutations were detected using this technique.

A mutation rate is not currently known for A. phagocytophilum.

We provide a curated database of 746 currently known genes, mutations in which cause ID (ID-associated genes [ID-AGs]), classified according to ID manifestation and associated clinical features.