Sentence examples for mutations creating a from inspiring English sources

In particular, while the two point mutations creating a novel cryptic splice site may be considered to be easily interpreted in terms of their effect on splicing, the small 18 bp deletion within intron 37 is quite peculiar.

The combined mutations created a remodeled SEC3-binding surface and yielded a Vβ domain with an affinity that was increased by 1000-fold (KD = 7 nM).

However, in other instances, mutations create a mutant protein ("poison peptide") which interferes with normal function or assumes a new function.

Several mutations create a premature stop codon in the open reading frame and therefore likely represent null alleles (Table 1, Figure 1A).

(2) Can co-existing mutations create a pharmacological obstacle that mediates drug resistance without functionally relieving the cells from addiction?

However, some mutations create a stop codon and hence no protein is encoded, or some mutations do not lead to stable proteins that can be detected by IHC.

Both mutations create a new frame that produces a slightly longer version of LF3 version (supplementary material S5, Supplementary Material online).

That is, multiple random mutations supposedly had accumulated before the gene was activated and thus before they could have experienced traditional natural selection, and these mutations created a whole, functioning gene.

The researchers believe the pepper's capsaicin-creating gene appeared after five mutations occurred during DNA replication, with the final mutation creating a functional copy.

These mice were bred to the Rb1ΔL mutation, creating a mixed 129/B6/FVB genetic background.

Sequences of all 6 mutants which were expressed at wild-type levels revealed a nonsense mutation creating a premature stop codon.