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Also compensatory mutations could reverse the biological cost [10].
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Wallace et al. (53) also showed that introduction of mitochondrial DNA mutations into non-tumorigenic cybrids could reverse the anti-tumorigenic effect of normal mitochondria leading to the conclusion that cancer can be best defined as a type of mitochondrial disease.
The report of Vaughan et al. indicated that aerobic glycolysis can be directly induced by an inflammatory microenvironment independent of additional genetic mutations and signals from adjacent cells, and curcumin could reverse this effect [ 6].
"Maybe You could reverse things?
–Money flows could reverse quickly.
This ratio could reverse over time.
The AV industry could reverse that.
By reverse-engineering any sort of analysis system, a post-processing program could reverse the effect.
Policy modifications could reverse this maldistribution.
The five key mutations could not be reversed first, because the receptor would be rendered useless.
Functional studies in Xenopus oocytes demonstrated that the mutant protein caused a hyperactive channel [ 81], and that the effects of the mutation could be partially reversed by quinidine, an antiarrhythmic drug that is a partial antagonist of the potassium channel encoded by KCNT1 [ 70, 82].
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