Sentence examples for mutations could influence from inspiring English sources

Thus, in a population of cells, genome-instability mutations could influence clonal evolution by establishing discrete mutational trajectories for genomes.

Therefore, we evaluated whether some of these mutations could influence the susceptibility to LL.

Considering all of the actionable genes as defined before (Table 4), deleterious mutations could influence sensitivity or resistance to treatments.

This modulation could occur in two ways: 1) the mutation could influence the local structural and dynamical properties of the apo state, exposing areas of the protein that make it prone to oligomerization through disulfide bond formation between the free cysteines of different SOD1 molecules [16].

The R100 residue is part of a surface patch involved in an intramolecular interaction of mature hNGF with its pro-domain [32], [36], [37] and therefore the R100W mutation could influence the structure of proNGF and its folding in the closed or extended configurations [36].

Evidently, the bzip63 mutation could influence the function of bZIP1, i.e. if we assumed that the bZIP1 functions as heterodimer with bZIP63.

As Est-6 has a physiological effect on cVA reception, we thus tested whether Est-6 mutation could influence cVA-triggered behaviors.

In particular, we hypothesized the T154A mutation could influence the conformation of the CT and thus availability of important protein interaction sites found within this region (Ponsaerts et al., 2012), leading us to next look at the CT tail.

To examine whether Est-6 mutation could influence cVA-induced behaviors, we first measured male-male sexual behavior by measuring the courtship index (CI) toward a CS target male.

The altered conformational flexibility, the degree of correlated motion between residues in the Fas DD, hydrogen bond formation within the CaM binding region, the contact number of each residue, and the electrostatic potential for the CaM binding region caused by the Fas DD V254N mutation could influence the van der Waals interactions and electrostatic interactions between CaM and the Fas DD.

This raises the possibility that changes in nucleotide composition, and more generally in the mutation spectrum could influence the estimation of variation in d N/d S or Kr/Kc and confound the correlation patterns of these two variables with LHT.