Sentence examples for mutations compared to from inspiring English sources

Both studies confirmed the lack of TP53 mutations compared to HPV- samples, and overall, a lower mutational burden in HPV+ disease.

Interestingly, old SCCs presented a higher fraction of signature 5 mutations compared to young SCCs (Fig. 1e).

Both chimpanzee and rhesus macaque showed significant numbers of frameshift mutations compared to self-genomes and suggest a need for further annotation.

In addition, old SCCs showed a higher ratio of non-synonymous (potentially impairing the function of the gene) over synonymous (neutral) mutations (Fig. 2d), meaning a higher number of potentially deleterious mutations compared to young SCCs.

All transformants from the original SCN1A vector were found to express the T1967A and G5923T mutations (compared to NM_006920.4), which encode the V650E and A1969S mutants in NaV1.1, respectively.

The most rigorous possible control would be a cell line that differ only with respect to disease mutations compared to the original cell line, i.e., otherwise isogenic cell lines.

The nuclear ldh sequence shows two non synonymous mutations compared to the classical P. ovale and four non synonymous mutations compared to the variant P. ovale (Table 3).

Spermatozoa exhibited a unique pattern of mutations compared to the liver.

Here, we determined significantly reduced ATP synthesis rates and cellular concentrations in patient cells with Parkin mutations compared to controls.

Design based on sequence alignments and computer modelling resulted in a humanized version bearing 13 mutations compared to initial murine scFv.

This is in line with Kastritis et al. [12], who also noted an underrepresentation of truncating mutations compared to the mutation spectrum in colorectal cancer.