Sentence examples for mutations clustered from inspiring English sources

The dendrogram showed that clones with either mutational object fell into clusters; that is, clones with rpoB mutations clustered into discrete groups, and likewise for clones bearing rho mutations.

Of these 51 mutations, 38 mutations clustered in exon-9 and the remaining 13 exon 20 (Table 1).

Chakrani, F. et al. Mutations clustered in exon 5 of the p53 gene in primary nasopharyngeal carcinomas from southeastern Asia.

The mutations clustered at the CpG-rich codons 153 through 158 of the p53 gene, and at codons 249 and 273 and had 100% of the guanines of the G to T transversions on the nontranscribed strand.

Thirty-three mutations were exclusively detected in the post-treatment samples and 13 mutations clustered into subclones that were dominant in the post-treatment compared to pre-treatment samples (Supplementary Data 6).

We recently demonstrated that inherited disease-causing mutations clustered in the α-helical coiled-coil "rod" domain of the muscle-specific intermediate filament (IF) protein desmin display a wide range of inhibitory effects on regular in vitro assembly.

Sequencing revealed that 7/42 (16.7%) harboured mutations clustering within 3 4 nucleotides upstream of the target PAM site.

Structurally, these mutations cluster around the active site cleft of the TK domain.

PIK3CA mutations cluster 90% in hotspots of exons 9 and 20, and affect the functionally important helical and kinase domains.

Since 80% of these mutations cluster within exons 9, 18 and 20, we focused on them and found no alterations.

The accumulated mutations differ across mutator strains, displaying base-substitution biases, allele-specific mutation hotspots, and break-associated mutation clustering.