Sentence examples for mutations caused a from inspiring English sources

In other words, when additional driver mutations caused a strong selective advantage, a mutator phenotype was not necessary for efficient tumorigenesis.

Neither lsy-2 nor lin-35 single mutations caused a larval arrest phenotype, while 100% of lin-35; lsy-2 double mutants (n = 93) arrested at the L1 stage.

None of the porin single or double mutations caused a decrease in susceptibility to the test compounds, implying that the compounds do not possess a strong porin preference, but instead can pass the outer membrane through a variety of routes.

W359F, Y377F and M375I mutations caused a reduction in steric interference, an alteration of subsite occupation and an increase in internal flexibility to accommodate longer donor/acceptor molecules for transglycosylation, resulting in an increase in the transglycosylation to hydrolysis ratio of up to 4.0-fold.

Mutations caused a change of allelic state to another allele within the set of possible alleles.

ΔN141 and ΔN197 mutations caused a marked accumulation of MHC-IIB in the posterior end of polarized cells.

Except for mutations causing a few disorders that we know are strongly associated with paternal age, we don't have a good understanding of what is going on".

When mutations cause a high population of ON or OFF states, or lead to an irreversible change in active site shape and dynamics, the allosteric diseases occur [13].

Genetic mutations cause a thickening of the wall of the heart, reducing its capacity to deal with accelerated heartbeats.

These mutations cause a reduction in O-mannosylation of α-dystroglycan, which results in WWS.

TPI mutations cause a rare metabolic syndrome, TPI deficiency.