Sentence examples for mutations can modify from inspiring English sources

The study shows that a handful of genetic mutations can modify a single receptor and ultimately fuel the creation of hundreds of species, according to Stephen Liberles, the Harvard Medical School biologist who oversaw the study.

LRRK2 contains both GTPase and kinase activities and certain familial mutations can modify one or other of these enzymatic activities [5], [11], [13] [19].

Mutations can modify the dependency of oncogene proteins for Hsp90 chaperoning.

It will be particularly interesting to test if CIC mutations can modify the tumour phenotypes of RB-deficient mice.

These mutations can modify the fitness of the genomes where they appear, adding further complexity to the process of interference, and making it difficult to fix any beneficial mutation and the emergence of a defined consensus sequence.

Compensatory mutations can modify the effect of various resistance mechanisms [reviewed by Maisnier-Patin and Andersson (2004) both in vitro (Schrag et al. 1997; Maisnier-Patin et al. 2002; Brandis et al. 2012) and in vivo (Björkman et al. 2000)].

Given the role of SynI in the modulation of release dynamics, we tested whether the Q555X mutation can modify the E/I balance and excitability at the network level by differentially altering basal transmission and/or STP paradigms in excitatory and inhibitory synapses.

Nonetheless the complex interaction of these markers with many other gene mutations that can modify the final prognostic impact, or the effect of intrinsic mutational characteristics, such as, allelic burden or mutation site on protein function and prognosis, make molecular risk stratification a highly complex process.

For females who carry the full mutation, the percentage of active X chromosomes with the normal repeat allele compared to the full mutation allele can modify the severity of the symptoms, as expected for any X-linked condition.

In microsatellites located within coding or promoter regions, mutations in the repeats can modify patterns of gene expression.

Modifications on genes structure, such as single mutation, deletions, or insertions can modify the interactions between the mutated gene product and its network partners (e.g. proteins participating in the same pathway), altering links of their network.