Sentence examples for mutations can induce from inspiring English sources

Such mutations can induce resistance to p53-mediated apoptosis, specially in response to cytotoxic drugs.

(59) This result is explained by our observation that such mutations can induce a population shift toward the S state.

The striking influence of indel variants on the molecular evolution of flanking sequences strengthens the emerging general view that mutations can induce further mutations.

It is obvious that the current knowledge of the mechanisms whereby mitochondrial mutations can induce and accelerate atherogenesis at the cellular and molecular level is insufficient.

Although N-terminal mutations can induce a prion state in HET-S (Coustou et al., 1999), our predictions suggests a sequence bias in HET-s permitting a more energetically favorable path for amyloid formation.

The lacZ coding sequence is the longest of the mutation reporter transgenes (3096 bp) and thus has many target nucleotide positions where mutations can induce the mutant phenotype, making it a very sensitive reporter.

We therefore suppose that the absence of PPARα binding on the CYP1A1 promoter after mutation can induce a conformational change of the promoter structure leading to a decrease of the activity of AhR on XRE sequences.

The Nkx3.1-null mutation can induce PIN at 6 months (31).

The rdd triple mutation can induce hyper-methylation in the 5′ and 3′ regions of the gene.

Therefore, lamins deficiency or mutation can induce unprotected telomeres and compromise the accumulation of DNA repair proteins, resulting in impaired DSB repair (Liu et al., 2005; Redwood et al., 2011).

However, with all the limitations due to the small sample size and to the lack of a specific assay in vitro assay, we can speculate, according to the data from Ko et al. [ 17], that the presence of the TET2 mutation can induce a second clone with a prominent monocytic differentiation.